00100 - Statement - Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 00200 - Statement - Consolidated Statements of Operations link:presentationLink link:calculationLink link:definitionLink 00300 - Statement - Consolidated Statements of Comprehensive Income (Loss) link:presentationLink link:calculationLink link:definitionLink 00400 - Statement - Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 40301 - Disclosure - Fair Value of Financial Instruments (Details) link:presentationLink link:calculationLink link:definitionLink 40304 - Disclosure - Fair Value of Financial Instruments (Details 4) link:presentationLink link:calculationLink link:definitionLink 40401 - Disclosure - Inventories (Details) link:presentationLink link:calculationLink link:definitionLink 40501 - Disclosure - Property and Equipment (Details) link:presentationLink link:calculationLink link:definitionLink 40701 - Disclosure - Accrued Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 41101 - Disclosure - Earnings per Share (Details) link:presentationLink link:calculationLink link:definitionLink 41301 - Disclosure - Commitments and Contingencies (Details) link:presentationLink link:calculationLink link:definitionLink 00090 - Document - Document and Entity Information link:presentationLink link:calculationLink link:definitionLink 00105 - Statement - Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 10101 - Disclosure - Organization and Business link:presentationLink link:calculationLink link:definitionLink 10201 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 10301 - Disclosure - Fair Value of Financial Instruments link:presentationLink link:calculationLink link:definitionLink 10401 - Disclosure - Inventories link:presentationLink link:calculationLink link:definitionLink 10501 - Disclosure - Property and Equipment link:presentationLink link:calculationLink link:definitionLink 10601 - Disclosure - Intangible Assets link:presentationLink link:calculationLink link:definitionLink 10701 - Disclosure - Accrued Liabilities link:presentationLink link:calculationLink link:definitionLink 10801 - Disclosure - Convertible Senior Secured Notes link:presentationLink link:calculationLink link:definitionLink 10901 - Disclosure - Summary Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 11001 - Disclosure - Share-Based Payments link:presentationLink link:calculationLink link:definitionLink 11101 - Disclosure - Earnings per Share link:presentationLink link:calculationLink link:definitionLink 11201 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 11301 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 11401 - Disclosure - Collaboration Agreements link:presentationLink link:calculationLink link:definitionLink 20202 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 30303 - Disclosure - Fair Value of Financial Instruments (Tables) link:presentationLink link:calculationLink link:definitionLink 30403 - Disclosure - Inventories (Tables) link:presentationLink link:calculationLink link:definitionLink 30503 - Disclosure - Property and Equipment (Tables) link:presentationLink link:calculationLink link:definitionLink 30603 - Disclosure - Intangible Assets (Tables) link:presentationLink link:calculationLink link:definitionLink 30703 - Disclosure - Accrued Liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 30803 - Disclosure - Convertible Senior Secured Notes (Tables) link:presentationLink link:calculationLink link:definitionLink 30903 - Disclosure - Summary Stockholders' Equity (Tables) link:presentationLink link:calculationLink link:definitionLink 31003 - Disclosure - Share-Based Payments (Tables) link:presentationLink link:calculationLink link:definitionLink 31103 - Disclosure - Earnings per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 31303 - Disclosure - Commitments and Contingencies (Tables) link:presentationLink link:calculationLink link:definitionLink 40101 - Disclosure - Organization and Business (Details) link:presentationLink link:calculationLink link:definitionLink 40201 - Disclosure - Summary of Significant Accounting Policies (Details) link:presentationLink link:calculationLink link:definitionLink 40202 - Disclosure - Summary of Significant Accounting Policies (Details 2) link:presentationLink link:calculationLink link:definitionLink 40203 - Disclosure - Summary of Significant Accounting Policies (Details 3) link:presentationLink link:calculationLink link:definitionLink 40302 - Disclosure - Fair Value of Financial Instruments (Details 2) link:presentationLink link:calculationLink link:definitionLink 40303 - Disclosure - Fair Value of Financial Instruments (Details 3) link:presentationLink link:calculationLink link:definitionLink 40601 - Disclosure - Intangible Assets (Details) link:presentationLink link:calculationLink link:definitionLink 40801 - Disclosure - Convertible Senior Secured Notes (Details) link:presentationLink link:calculationLink link:definitionLink 40901 - Disclosure - Summary Stockholders' Equity (Details) link:presentationLink link:calculationLink link:definitionLink 41001 - Disclosure - Share-Based Payments (Details) link:presentationLink link:calculationLink link:definitionLink 41002 - Disclosure - Share-Based Payments (Details 2) link:presentationLink link:calculationLink link:definitionLink 41003 - Disclosure - Share-Based Payments (Details 3) link:presentationLink link:calculationLink link:definitionLink 41201 - Disclosure - Income Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 41401 - Disclosure - Collaboration Agreements (Details) link:presentationLink link:calculationLink link:definitionLink