Accounting Policies [Abstract] Pre-launch inventory Pre-launch Inventory, Net Pre-launch Inventory, Net Receivables [Abstract] Allowance for expected sales discounts and allowances Allowance for Expected Sales deductions Represents the allowance for sales discounts related to prompt-pay discounts and contractual fee for service arrangements to wholesalers and distributors. Disaggregation of Revenue [Abstract] Disaggregated Revenues Revenue from Contract with Customer [Text Block] Fair Value Disclosures [Abstract] Fair Value, Recurring and Nonrecurring [Table] Fair Value, Recurring and Nonrecurring [Table] Financial Instrument [Axis] Financial Instrument [Axis] Financial Instruments [Domain] Financial Instruments [Domain] Cash Cash [Member] Money market funds Money Market Funds [Member] Corporate debt securities Corporate Debt Securities [Member] Municipal debt securities Municipal Bonds [Member] U.S. government agency debt securities US Government Agencies Debt Securities [Member] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV [Domain] Quoted Prices in Active Markets for Identical Assets (Level 1) Fair Value, Inputs, Level 1 [Member] Significant Other Observable Inputs (Level 2) Fair Value, Inputs, Level 2 [Member] Measurement Basis [Axis] Measurement Basis [Axis] Fair Value Measurement [Domain] Fair Value Measurement [Domain] Portion at Fair Value Measurement Portion at Fair Value Measurement [Member] Total Fair Value Reported Value Measurement [Member] Measurement Frequency [Axis] Measurement Frequency [Axis] Measurement Frequency [Domain] Measurement Frequency [Domain] Recurring Fair Value, Recurring [Member] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Assets: Assets, Fair Value Disclosure [Abstract] Cash and cash equivalents Cash and Cash Equivalents, Fair Value Disclosure Short-term marketable securities Debt Securities, Available-for-sale, Current Municipal debt securities Debt Securities, Noncurrent [Abstract] Long-term marketable securities Debt Securities, Available-for-sale, Noncurrent U.S. government agency debt securities Other Assets, Noncurrent [Abstract] Other noncurrent assets Assets for Plan Benefits, Defined Benefit Plan Total assets at fair value Assets, Fair Value Disclosure Statement of Comprehensive Income [Abstract] Net earnings Net Income (Loss) Attributable to Parent Other comprehensive earnings (loss) Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Unrealized gain (loss) on marketable securities, net of tax Other Comprehensive Income (Loss), Available-for-sale Securities Adjustment, Net of Tax, Portion Attributable to Parent Other comprehensive earnings (loss) Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Comprehensive earnings Comprehensive Income (Loss), Net of Tax, Attributable to Parent Fair Value (Level 3) Fair Value, Inputs, Level 3 [Member] Assets Concentration Risk [Table] Concentration Risk [Table] Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Domain] Concentration Risk Benchmark [Domain] Revenues Revenue Benchmark [Member] Accounts Receivable, net Accounts Receivable [Member] Concentration Risk Type [Axis] Concentration Risk Type [Axis] Concentration Risk Type [Domain] Concentration Risk Type [Domain] Customer Concentration Risk Customer Concentration Risk [Member] Customer [Axis] Customer [Axis] Customer [Domain] Customer [Domain] Customer A Customer A [Member] Represents Customer A. Customer B Customer B [Member] Represents Customer B. Customer C Customer C [Member] Represents Customer C. Concentration risk percentage Concentration Risk [Line Items] Accounts Receivable, Net Accounts Receivable, after Allowance for Credit Loss [Abstract] Allowance for doubtful accounts Accounts Receivable, Allowance for Credit Loss Accounts receivable written off Accounts Receivable, Allowance for Credit Loss, Writeoff Concentration risk percentage Concentration Risk, Percentage Retirement Benefits [Abstract] Employee Benefit Plan Pension and Other Postretirement Benefits Disclosure [Text Block] Inventory Disclosure [Abstract] Inventories Inventory Disclosure [Text Block] Organization and Nature of Operations Organization and Nature of Operations Nature of Operations [Text Block] Debt Disclosure [Abstract] Schedule of Long-term Debt Instruments [Table] Schedule of Long-term Debt Instruments [Table] Long-term Debt, Type [Axis] Long-term Debt, Type [Axis] Long-term Debt, Type [Domain] Long-term Debt, Type [Domain] 2023 Notes Percentage Of0.625 Convertible Senior Notes Due2023 [Member] Represents information pertaining to 0.625% Convertible Senior Notes due 2023. Debt Instrument [Line Items] Debt Instrument [Line Items] Principal amount of the 2023 Notes Debt Instrument, Face Amount Unamortized debt discount and deferred financing costs Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net Carrying value of the convertible notes Convertible Notes Payable, Noncurrent Schedule of fair value of the financial assets and liabilities Fair Value, Assets Measured on Recurring and Nonrecurring Basis [Table Text Block] Schedule of unrestricted marketable securities Schedule of Available-for-sale Securities Reconciliation [Table Text Block] Schedule of contractual maturities of the unrestricted available for sale marketable securities held Investments Classified by Contractual Maturity Date [Table Text Block] Schedule of financial liabilities that are not carried at fair value Fair Value, Liabilities Measured on Recurring and Nonrecurring Basis [Table Text Block] Fair Value of Financial Instruments Fair Value Disclosures [Text Block] Income Tax Disclosure [Abstract] Balance at beginning of period Unrecognized Tax Benefits Gross increases related to current year tax positions Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions Gross increases related to prior year tax positions Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions Gross decreases related to prior year tax positions Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions Lapse of statute of limitations Unrecognized Tax Benefits, Reduction Resulting from Lapse of Applicable Statute of Limitations Change in tax rates Unrecognized Tax Benefits Change in Tax Rates Amount of increase (decrease) in unrecognized tax benefits resulting from changes in tax rates. Balance at end of period Operating Loss Carryforwards [Table] Operating Loss Carryforwards [Table] Income Tax Authority [Axis] Income Tax Authority [Axis] Income Tax Authority [Domain] Income Tax Authority [Domain] U.S. Federal Domestic Tax Authority [Member] State State and Local Jurisdiction [Member] Operating Loss Carryforwards [Line Items] Operating Loss Carryforwards [Line Items] NOL carryforwards Operating Loss Carryforwards NOLs utilized Net Operating Loss Carryforward Utilized The amount of net operating loss carryforwards that were utilized to reduce taxable income under enacted tax laws. Research and development credit carryforwards Tax Credit Carryforward, Amount Alternate minimum tax expense on uncertain tax position Income Tax Expense on Uncertain Tax Position, Alternate Minimum Tax The amount Of income tax expense on uncertain tax position, alternate minimum tax. Tax expense on uncertain tax positions Income Tax Expense on Uncertain Tax Position The amount represents the income tax expense on uncertain tax position. Property, Plant and Equipment [Abstract] Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Property, Plant and Equipment, Type [Axis] Property, Plant and Equipment, Type [Axis] Property, Plant and Equipment, Type [Domain] Property, Plant and Equipment, Type [Domain] Lab equipment and furniture Lab Equipment And Furniture [Member] Represents information pertaining to lab equipment and furniture. Leasehold improvements Leasehold Improvements [Member] Software Computer Software, Intangible Asset [Member] Computer equipment Computer Equipment [Member] Construction-in-progress Construction in Progress [Member] Property and equipment Property, Plant and Equipment [Line Items] Property and equipment, gross Property, Plant and Equipment, Gross Less accumulated depreciation and amortization Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Property and equipment, net Property, Plant and Equipment, Net Depreciation and amortization expense Depreciation, Depletion and Amortization, Nonproduction Accrued Product Returns and Rebates No definition available. Accrued rebates Accrued Rebates Represents the amount of accrued rebates. Accrued product returns Accrued Product Returns Represents the amount of accrued product returns. Total Accrued Product Returns and Rebates. Carrying value as of the balance sheet date of accrued product returns and rebates. Summary of disaggregation of revenue by nature Disaggregation of Revenue [Table Text Block] Schedule of accrued sales deductions Schedule of Accrued Product Returns and Rebates [Table Text Block] Tabular disclosure of the accrued product returns and rebates. Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Statement of Financial Position [Abstract] Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Common stock, shares authorized (in shares) Common Stock, Shares Authorized Common stock, shares issued (in shares) Common Stock, Shares, Issued Common stock, shares outstanding (in shares) Common Stock, Shares, Outstanding Maximum contractual term Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period Threshold limit for medical claim Threshold Limit For Medical Claim The stop-loss limit of exposure to the Entity, per employee per year, for self-insured employee medical claims. Stop-loss limit for self-insured employee medical claims Self-Insurance Liability The amount payable on self-insured employee medical claims net of the coverage provided from stop-loss insurance. Other Income and Expenses [Abstract] Other (Expense) Income Other Nonoperating Income and Expense [Text Block] Leases [Abstract] Operating leases, weighted-average remaining lease term in years Operating Lease, Weighted Average Remaining Lease Term Operating leases, weighted-average discount rate Operating Lease, Weighted Average Discount Rate, Percent Leases Lease Disclosure [Text Block] The entire disclosure of information about leases. Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Use of Estimates Use of Estimates, Policy [Policy Text Block] Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Marketable Securities Marketable Securities, Policy [Policy Text Block] Accounts Receivable, net Accounts Receivable [Policy Text Block] Concentration of Credit Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Inventories Inventory, Policy [Policy Text Block] Intangible Assets Intangible Assets, Finite-Lived, Policy [Policy Text Block] Impairment of Long-Lived Assets Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block] Deferred Financing Costs Deferred Financing Costs [Policy Text Block] Represent the disclosure of accounting policy for the deferred financing costs. Revenue Recognition Revenue from Contract with Customer [Policy Text Block] Cost of Goods Sold Cost of Goods and Service [Policy Text Block] Research and Development Expenses and Related Accrued Research and Development Expenses Research And Development Expenses And Related Accrued Research And Development Expenses [Policy Text Block] Research And Development Expenses And Related Accrued Research And Development Expenses [Policy Text Block] Share-Based Compensation Share-based Payment Arrangement [Policy Text Block] Self-insurance Liabilities Self Insurance Reserve [Policy Text Block] Leases Lessee, Leases [Policy Text Block] Advertising Expense Advertising Cost [Policy Text Block] Income Taxes Income Tax, Policy [Policy Text Block] Recently Issued Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Sale of Stock [Axis] Sale of Stock [Axis] Sale of Stock [Domain] Sale of Stock [Domain] Overallotment option Over-Allotment Option [Member] Convertible Senior Notes due 2023 granted to initial purchasers Percentage Of0.625 Convertible Senior Notes Due2023 Granted To Initial Purchasers [Member] Represents information pertaining to the 0.625% Convertible Senior Notes due 2023 that were granted to the initial purchasers. Convertible Senior Notes due 2023 over-allotment option Percentage Of0.625 Convertible Senior Notes Due2023 Over Allotment Option [Member] Represents information pertaining to the 0.625% Convertible Senior Notes due in 2023 that were granted in the over-allotment option to purchase. Notes payable Over-allotment period for additional principal amount Over-allotment period for Additional Principal Amount Over-allotment period for additional principal amount for Notes due 2023. Interest rate (as a percent) Debt Instrument, Interest Rate, Stated Percentage Threshold trading days (whether or not consecutive) Debt Instrument, Convertible, Threshold Trading Days Consecutive trading day period (in days) Debt Instrument, Convertible, Threshold Consecutive Trading Days Minimum percentage of the conversion price on trading day Debt Instrument, Convertible, Threshold Percentage of Stock Price Trigger Conversion option stock price trigger Debt Instrument, Convertible, Stock Price Trigger Threshold trading days period prior to a conversion date during which principal amount of notes for such trading day was less than 98% of the product of the last reported sale price of common stock Debt Instrument Convertible Threshold Trading Days was Less Than Specified Percentage of Product of Last Reported Sale Price of Common Stock Threshold number of specified trading days prior to a conversion date during which principal amount of notes for such trading day was less than specified percentage of product of last reported sale price of common stock, that common stock price to conversion price of convertible debt instruments must exceed threshold percentage within a specified consecutive trading period to trigger conversion feature. Consecutive trading day period prior to a conversion date during which principal amount of notes for such trading day was less than 98% of the product of the last reported sale price of common stock Debt Instrument Convertible Threshold Consecutive Trading Days was Less Than Specified Percentage of Product Last Reported Sale Price of Common Stock Threshold period of specified consecutive trading days prior to a conversion date during which principal amount of notes for such trading day was less than the specified percentage of the product of the last reported sale price of common stock, within which common stock price to conversion price of convertible debt instruments must exceed threshold percentage for a specified number of trading days to trigger conversion feature. Percentage of last reported sales price threshold per $1,000 principal amount Debt Instrument, Covenant, Percentage Of Last Reported Sales Price Threshold Per $1,000 Principal Amount Debt Instrument, Covenant, Percentage Of Last Reported Sales Price Threshold Per $1,000 Principal Amount Conversion rate for the notes (in shares per $1,000 principal amount) Debt Instrument, Convertible, Conversion Ratio Conversion price, per share of common stock Debt Instrument, Convertible, Conversion Price Amount of principal value to be repaid Notes Face Value The amount of face value of notes issued. Convertible note hedge options issued (in shares) Debt Conversion, Converted Instrument, Warrants or Options Issued Shares of common stock issued upon conversion of Notes Debt Conversion, Converted Instrument, Shares Issued Total cost of the convertible note hedge transactions Purchases Of Convertible Note Hedge The cash outflow representing the total cost of the convertible note hedge transactions. Warrants issued Class of Warrant or Right, Outstanding Number of shares per warrant Class of Warrant or Right, Number of Shares in Which Holder Can be Entitled per Warrants at Strike Price Represents the information pertaining to the shares per warrant entitled to holders at strike price. Strike price of the warrant transactions (in dollars per share) Class of Warrant or Right, Exercise Price of Warrants or Rights Proceeds from sale of warrants Proceeds from Issuance of Warrants Debt discount Unamortized Debt Issuance Expense Effective interest rate (as percent) Debt Instrument, Interest Rate, Effective Percentage Debt financing costs Payment of Financing and Stock Issuance Costs Conversion option reported as debt discount and APIC Adjustments to Additional Paid in Capital, Convertible Debt with Conversion Feature and Debt Discount Conversion option that has been reported as an adjustment to additional paid in capital (APIC) including conversion feature and debt discount. Deferred financing costs Debt Issuance Costs, Net Debt converted Debt Conversion, Original Debt, Amount 0.625% Convertible Senior Notes due 2023 Convertible Notes Payable [Member] Deferred Financing Costs Debt Instrument, Interest Rate, Stated Percentage [Abstract] Earnings Per Share [Abstract] Schedule of common stock equivalents excluded in the calculation of diluted earnings per share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of computation of basic and diluted net earnings per share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Share-based Payment Arrangement [Abstract] Stockholders' Equity Stockholders' Equity Note Disclosure [Text Block] Summary of liability component of 2023 Notes Convertible Debt [Table Text Block] Schedule of Other (Expenses) Income Schedule of Other Nonoperating Income (Expense) [Table Text Block] Interest income Interest Income, Other Interest expense Interest Expense Interest expense on nonrecourse liability related to sale of future royalties Interest Expense, Other Changes in fair value of derivative liabilities Derivative, Gain (Loss) on Derivative, Net Loss on extinguishment of debt Gain (Loss) on Extinguishment of Debt Total Other Nonoperating Income (Expense) Amortization of deferred financing costs and debt discount Amortization of Debt Issuance Costs and Discounts Goodwill and Intangible Assets Disclosure [Abstract] Schedule of Finite-Lived Intangible Assets [Table] Schedule of Finite-Lived Intangible Assets [Table] Statistical Measurement [Axis] Statistical Measurement [Axis] Statistical Measurement [Domain] Statistical Measurement [Domain] Minimum Minimum [Member] Maximum Maximum [Member] Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets, Major Class Name [Domain] Finite-Lived Intangible Assets, Major Class Name [Domain] Patent Defense Costs Patent Defense Costs [Member] Represents information concerning the capitalized patent defense costs related to the Watson litigation. Finite-Lived Intangible Assets [Line Items] Finite-Lived Intangible Assets [Line Items] Intangible assets, weighted-average life Acquired Finite-lived Intangible Assets, Weighted Average Useful Life Intangible assets, gross Finite-Lived Intangible Assets, Gross Less accumulated amortization Finite-Lived Intangible Assets, Accumulated Amortization Intangible assets, net Intangible Assets, Net (Excluding Goodwill) Amortized cost Debt Securities, Available-for-sale, Amortized Cost Gross unrealized gains Debt Securities, Available-for-sale, Accumulated Gross Unrealized Gain, before Tax Gross unrealized losses Debt Securities, Available-for-sale, Accumulated Gross Unrealized Loss, before Tax Total fair value Debt Securities, Available-for-sale Minimum age requirement for employees to participate in the plan Defined Contribution Plan Eligibility Minimum Age Represents the minimum eligibility age for employees to participate in the defined contribution plan. Maximum contribution by employee (as a percent) Defined Contribution Plan, Maximum Annual Contributions Per Employee, Percent Employer match of employee contributions on the first level of salary deferral (as a percent) Defined Contribution Plan Employer Match Level One Represents the employer matching contribution of the first level of employee contributions. Percentage of eligible compensation, first level, matched by employer Defined Contribution Plan Employer Match Employee Contribution Level One Represents the first level of employee contributions (percentage of compensation), which are matched by the employer. Employer match of employee contributions on the second level of salary deferral (as a percent) Defined Contribution Plan Employer Match Level Two Represents the employer matching contribution of the second level of employee contributions. Percentage of eligible compensation, second level, partially matched by employer Employer Match Employee Contribution Level Two Represents the second level of employee contributions (percentage of compensation), which are partially matched by the employer. Maximum percentage of participating employee annual compensation that the company may elect to make a discretionary contribute towards Defined Contribution Plan, Maximum Discretionary Employer Contribution Percentage Represents the maximum percentage of participating employee annual compensation, that the employer may discretionary decide to contribute to a defined contribution plan. Company's contribution to the 401(k) Plan Defined Contribution Plan, Cost Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Counterparty Name [Axis] Counterparty Name [Axis] Counterparty Name [Domain] Counterparty Name [Domain] Advent Key West, LLC (Landlord) Advent Key West Llc [Member] Represents the information pertaining to Advent Key West, LLC. Lessee, Lease, Description [Line Items] Lessee, Lease, Description [Line Items] Optional lease renewal term Lessee, Operating Lease, Renewal Term Initial fixed monthly rental rate Operating Leases, Rental Expenses, Initial Fixed Monthly Rental Payments The amount of fixed monthly rental payments due under the lease agreement. Increase in fixed monthly rental payments Operating Leases, Rental Expenses, Annual increase in Rental Payments, Percentage The percentage of increase in fixed monthly rental payments on each anniversary of the lease commencement date. Required security deposit Security Deposit Tenant improvement allowance Operating Leases Additional Allowance for Tenant and Capital Improvement Represents the additional amount of payments that the lessee can elect to make in connection with tenant and capital improvement allowances under the terms of an agreement classified as an operating lease. Revenue, Initial Application Period Cumulative Effect Transition [Table] Revenue, Initial Application Period Cumulative Effect Transition [Table] Trokendi Xr Trokendi Xr [Member] Represents information pertaining to Trokendi XR patent litigation. Product and Service [Axis] Product and Service [Axis] Product and Service [Domain] Product and Service [Domain] Net product sales Product [Member] Trokendi XR Oxtellar XR Oxtellar X R [Member] Represents information pertaining to Oxtellar XR product. Royalty revenue Royalty [Member] Licensing revenue License [Member] Revenue Recognition Revenue, Initial Application Period Cumulative Effect Transition [Line Items] Total revenues Revenues Noncash royalty revenue Revenue From Royalty Agreement Represents revenue from the sale of certain royalty and milestone rights. Schedule of customers that represent more than 10% total revenue and more than 10% of accounts receivable, net Schedules of Concentration of Risk, by Risk Factor [Table Text Block] Schedule of New Accounting Pronouncements and Changes in Accounting Principles Schedule of New Accounting Pronouncements and Changes in Accounting Principles [Table Text Block] Schedule of share-based compensation expense Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Schedule of assumptions used in estimation of fair value of each award option on the date of grant using Black-Scholes option-pricing model Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Summary of stock option and SAR activity Share-based Payment Arrangement, Option, Activity [Table Text Block] Income Statement [Abstract] Statement [Table] Statement [Table] Statement [Line Items] Statement [Line Items] Revenue Revenues [Abstract] Costs and expenses Costs and Expenses [Abstract] Cost of goods sold Cost of Goods and Services Sold Research and development Research and Development Expense Selling, general and administrative Selling, General and Administrative Expense Total costs and expenses Costs and Expenses Operating earnings Operating Income (Loss) Other (expense) income Other Nonoperating Income (Expense) [Abstract] Interest expense Other Nonoperating Expense Interest income, net Other Nonoperating Income Earnings before income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Income tax expense Income Tax Expense (Benefit) Net earnings Earnings per share: Earnings Per Share, Basic and Diluted [Abstract] Basic (in dollars per share) Earnings Per Share, Basic Diluted (in dollars per share) Earnings Per Share, Diluted Weighted-average shares outstanding Weighted Average Number of Shares Outstanding, Diluted [Abstract] Basic (in shares) Weighted Average Number of Shares Outstanding, Basic Diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Rent expense Operating Leases, Rent Expense Year ending December 31: Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract] 2019 Operating Leases, Future Minimum Payments Due, Next Twelve Months 2020 Operating Leases, Future Minimum Payments, Due in Two Years Thereafter Operating Leases Future Minimum Payments Thereafter Due Amount of required minimum rental payments for operating leases having an initial or remaining non-cancelable lease term in excess of one year due after the second fiscal year following the latest fiscal year. Excludes interim and annual periods when interim periods are reported on a rolling approach, from latest balance sheet date. Total Operating Leases, Future Minimum Payments Due Accrued Product Returns and Rebates Accrued Product Returns and Rebates [Text Block] The entire disclosure for accrued product returns and rebates. Accounts Receivable Loans, Notes, Trade and Other Receivables Disclosure [Text Block] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] License and collaboration agreements Collaborative Arrangement [Member] Royalty revenue agreements Royalty Agreements [Member] Contract assets Contract with Customer, Asset, after Allowance for Credit Loss Contract liabilities Contract with Customer, Liability Sales return period prior to expiry date Sales Return Period Prior To Expiration Represents the period within which a product can be returned by the customers to the entity prior to the expiry date. Sales return period subsequent to expiry date Sales Return Period Represents the period within which a product can be returned by the customers to the entity subsequent to the expiry date. Number of commercial products Number Of Commercial Products Represents the number of commercial products. Product shelf life Products, Shelf Life Represents the period within which a product can be expired. Guaranteed minimum amounts Minimum Guaranteed Amounts Owed to Company Minimum guaranteed amount owed to company from license and royalty revenue. Payables and Accruals [Abstract] Schedule of accrued expenses and other current liabilities Schedule of Accrued Liabilities [Table Text Block] Lease assets Operating Lease, Right-of-Use Asset Lease liabilities, current Operating Lease, Liability, Current Lease liabilities, long term Operating Lease, Liability, Noncurrent Total lease liabilities Lessee Operating Lease Liabilities Amount of current and non-current operating lease liabilities. Accrued clinical trial costs Accrued Clinical Trial and Clinical Supply Costs Current Represents the amount of clinical trial and clinical supply costs accrued. Accrued compensation Employee-related Liabilities, Current Accrued professional fees Accrued Professional Fees, Current Lease liabilities, current Interest Payable, Current Other accrued expenses Other Accrued Liabilities, Current Total Accrued Liabilities, Current Assets Assets [Abstract] Current assets Assets, Current [Abstract] Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Marketable securities Marketable Securities, Current Accounts receivable, net Accounts Receivable, after Allowance for Credit Loss, Current Inventories, net Inventory, Net Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Total current assets Assets, Current Long term marketable securities Marketable Securities, Noncurrent Property and equipment, net Intangible assets, net Lease assets Deferred income taxes Deferred Income Tax Assets, Net Other assets Other Assets, Noncurrent Total assets Assets Liabilities and stockholders’ equity Liabilities and Equity [Abstract] Current liabilities Liabilities, Current [Abstract] Accounts payable Accounts Payable, Current Accrued product returns and rebates Accrued expenses and other current liabilities Other Accounts Payable and Accrued Liabilities Income taxes payable Accrued Income Taxes, Current Nonrecourse liability related to sale of future royalties; current portion Non Recourse Debt Sale of Future Royalties Current Current portion of debt due within one year or the normal operating cycle, if longer, related to the sale of future royalties, for which the creditor does not have general recourse to the debtor but rather has recourse only to the property used for collateral in the transaction or other specific property. Total current liabilities Liabilities, Current Convertible notes, net Nonrecourse liability related to sale of future royalties; long term Non Recourse Debt Sale of Future Royalties Noncurrent Noncurrent portion of debt, net of the amount due within one year or the normal operating cycle, if longer, related to the sale of future royalties, for which the creditor does not have general recourse to the debtor but rather has recourse only to the property used for collateral in the transaction or other specific property. Other liabilities Other Liabilities, Noncurrent Total liabilities Liabilities Stockholders’ equity Stockholders' Equity Attributable to Parent [Abstract] Common stock, $0.001 par value; 130,000,000 shares authorized; 52,533,348 and 52,316,583 shares issued and outstanding as of December 31, 2019 and December 31, 2018, respectively Common Stock, Value, Issued Additional paid-in capital Additional Paid in Capital Accumulated other comprehensive earnings (loss), net of tax Accumulated Other Comprehensive Income (Loss), Net of Tax Retained earnings Retained Earnings (Accumulated Deficit) Total stockholders’ equity Stockholders' Equity Attributable to Parent Total liabilities and stockholders’ equity Liabilities and Equity Convertible Senior Notes Due 2023 Long-term Debt [Text Block] Cover page. Document Type Document Type Document Annual Report Document Annual Report Document Period End Date Document Period End Date Entity File Number Entity File Number Document Transition Report Document Transition Report Entity Registrant Name Entity Registrant Name Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Tax Identification Number Entity Address, Address Line One Entity Address, Address Line One Entity Address, City or Town Entity Address, City or Town Entity Address, State or Province Entity Address, State or Province Entity Address, Postal Zip Code Entity Address, Postal Zip Code City Area Code City Area Code Local Phone Number Local Phone Number Title of 12(b) Security Title of 12(b) Security Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Trading Symbol Trading Symbol Security Exchange Name Security Exchange Name Entity Well-known Seasoned Issuer Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Voluntary Filers Entity Current Reporting Status Entity Current Reporting Status Entity Interactive Data Current Entity Interactive Data Current Entity Filer Category Entity Filer Category Entity Small Business Entity Small Business Entity Emerging Growth Company Entity Emerging Growth Company Entity Shell Company Entity Shell Company Entity Public Float Entity Public Float Documents Incorporated by Reference Documents Incorporated by Reference [Text Block] Entity Central Index Key Entity Central Index Key Amendment Flag Amendment Flag Current Fiscal Year End Date Current Fiscal Year End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Schedule of summary of the income tax expense (benefit) Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] Schedule of reconciliation of income tax expense at the U.S Federal statutory income tax rate to the entity's effective income tax rate Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Schedule of significant components of the entity's deferred tax assets (liabilities) Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Schedule of reconciliation of the beginning and ending amount of gross unrecognized tax benefits Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block] Schedule of gross carrying amount and related accumulated amortization of the intangible assets Schedule of Acquired Finite-Lived Intangible Assets by Major Class [Table Text Block] Schedule of property and equipment Schedule of Property Plant and Equipment Components [Table Text Block] Tabular disclosure of the components of property, plant and equipment. Current Current Income Tax Expense (Benefit), Continuing Operations [Abstract] Federal Current Federal Tax Expense (Benefit) State Current State and Local Tax Expense (Benefit) Deferred Deferred Income Tax Expense (Benefit), Continuing Operations [Abstract] Federal Deferred Federal Income Tax Expense (Benefit) State Deferred State and Local Income Tax Expense (Benefit) Income tax expense Income tax expense computed at U.S. Federal statutory income tax rate Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount State income taxes Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount Permanent items Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount Research and development credits Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount Uncertain income tax position Effective Income Tax Rate Reconciliation, Tax Contingency, Amount Effect of rate changes Effective Income Tax Rate Reconciliation, Change in Enacted Tax Rate, Amount Other Effective Income Tax Rate Reconciliation, Other Adjustments, Amount 2020 Lessee, Operating Lease, Liability, Payments, Due Next Twelve Months 2021 Lessee, Operating Lease, Liability, Payments, Due Year Two 2022 Lessee, Operating Lease, Liability, Payments, Due Year Three 2023 Lessee, Operating Lease, Liability, Payments, Due Year Four Thereafter Lessee, Operating Lease, Liability, Payments, Due Thereafter Lessee, Operating Lease, Liability, Payments, Due Thereafter Total future minimum lease payments Lessee, Operating Lease, Liability, Payments, Due Less: imputed interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount Present value of lease liabilities Operating Lease, Liability Property and Equipment Property, Plant and Equipment Disclosure [Text Block] New Accounting Pronouncements or Change in Accounting Principle [Table] New Accounting Pronouncements or Change in Accounting Principle [Table] Initial Application Period Cumulative Effect Transition [Axis] Initial Application Period Cumulative Effect Transition [Axis] Initial Application Period Cumulative Effect Transition [Domain] Initial Application Period Cumulative Effect Transition [Domain] Difference between Revenue Guidance in Effect before and after Topic 606 Difference between Revenue Guidance in Effect before and after Topic 606 [Member] Calculated under Revenue Guidance in Effect before Topic 606 [Member] Calculated under Revenue Guidance in Effect before Topic 606 [Member] Adjustments for New Accounting Pronouncements [Axis] Adjustments for New Accounting Pronouncements [Axis] Type of Adoption [Domain] Type of Adoption [Domain] ASU 2016-02 Accounting Standards Update 2016-02 [Member] ASU 2014-09 Accounting Standards Update 2014-09 [Member] New Accounting Pronouncements or Change in Accounting Principle [Line Items] New Accounting Pronouncements or Change in Accounting Principle [Line Items] Accounts receivable, net Deferred income taxes (asset) Deferred Tax Assets, Net, Noncurrent Liabilities Liabilities [Abstract] Deferred licensing revenue Deferred Revenue, Current Deferred licensing revenue, net of current portion Deferred Revenue, Noncurrent Equity Equity [Abstract] Accumulated deficit Lease liabilities Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Stock options (in shares) Share-based Payment Arrangement, Option [Member] Income per share Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Common stock equivalents excluded in the calculation of diluted income per share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Net Income (Loss) Available to Common Stockholders, Basic [Abstract] Net Income (Loss) Available to Common Stockholders, Basic [Abstract] Net earnings Net Income (Loss) Available to Common Stockholders, Basic Interest expense on Convertible Senior Secured Notes due 2019 Interest on Convertible Debt, Net of Tax Changes in fair value of derivative liabilities Increase Decrease in Fair Value Derivative Liabilities The increase (decrease) during the period in the fair value of derivative instruments reported as liabilities. Loss on extinguishment of debt Gains Losses On Extinguishment of Outstanding Debt Difference between the fair value of payments made and the carrying amount of outstanding debt which is extinguished prior to maturity. Loss on extinguishment of outstanding debt, as if converted Gains Losses on Extinguishment of Outstanding Debt as if Converted Difference between the fair value of payments made and the carrying amount of outstanding debt as if converted which is extinguished prior to maturity. Total adjustments Dilutive Securities, Effect on Basic Earnings Per Share Net earnings used for calculation of diluted EPS Net Income (Loss) Attributable to Parent, Diluted Weighted Average Number of Shares Outstanding, Basic [Abstract] Weighted Average Number of Shares Outstanding, Basic [Abstract] Weighted average shares outstanding, basic (in shares) Incremental Weighted Average Shares Attributable to Dilutive Effect [Abstract] Incremental Weighted Average Shares Attributable to Dilutive Effect [Abstract] Shares underlying Convertible Senior Notes (in shares) Incremental Common Shares Attributable to Dilutive Effect of Conversion of Debt Securities Shares issuable to settle interest make-whole derivatives (in shares) Incremental Common Shares Attributable To Settlement Of Interest Make Whole Derivatives Represents the information relating to shares issuable to settle interest make-whole derivatives. Stock options and SAR (in shares) Incremental Common Shares Attributable to Dilutive Effect of Share-based Payment Arrangements Total dilutive potential common shares (in shares) Weighted Average Number Diluted Shares Outstanding Adjustment Weighted average shares outstanding, diluted (in shares) Earnings per share, basic (in dollars per share) Earnings per share, diluted (in dollars per share) Fair Value Convertible Debt, Fair Value Disclosures Quarterly Financial Information Disclosure [Abstract] Schedule of quarterly financial information Quarterly Financial Information [Table Text Block] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Plan Name [Axis] Plan Name [Axis] Plan Name [Domain] Plan Name [Domain] 2012 Plan Equity Incentive Plan2012 [Member] Represents information pertaining to the 2012 Equity Incentive Plan that provides for grants of stock options, purchase rights and awards to employees, officers, directors, consultants or advisors. Employee Stock Purchase Plan Employee Stock Purchase Plan [Member] Represents the information pertaining to employee stock purchase plan. Award Type [Axis] Award Type [Axis] Award Type [Domain] Award Type [Domain] Stock Option Title of Individual [Axis] Title of Individual [Axis] Title of Individual [Domain] Title of Individual [Domain] Employees, Consultants and Advisors Employees Consultants And Advisors [Member] This member represents information pertaining to employees, consultants and advisors Directors Director [Member] Share-Based Compensation Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Number of votes to which holders of common shares are entitled for each share held Number of Votes Per Common Share Held Represents the number of votes to which the holders of common stock are entitled for each share held. Maximum number of shares of common stock provided for issuance Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized Number of annual installments in which the awards would generally vest starting on the first anniversary of the date of grant Share Based Compensation Arrangement by Share Based Payment Award, Award Vesting Number of Installments from First Anniversary of Grant Date Represents the number of installments in which the awards would generally vest starting from the first anniversary of the date of grant. Contractual term Purchase price percentage Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent Vesting period Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period Number of operating segments Number of Operating Segments Schedule of balance sheet information related to leases Lease Balance Sheet Disclosure [Table Text Block] Tabular disclosure of balance sheet information related to leases. Schedule of lease costs and supplemental cash flow information Lease, Cost [Table Text Block] Schedule of weighted average remaining lease term and discount rate information Lease Quantitative Disclosure [Table Text Block] Tabular disclosure of Weighted average lease term and discount rate. Schedule of maturities of operating lease liabilities Lessee, Operating Lease, Liability, Maturity [Table Text Block] Schedule of future minimum lease payments under non-cancelable operating leases Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block] Revenues Total costs and expenses Operating earnings Statement of Stockholders' Equity [Abstract] Equity Components [Axis] Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Common Stock Common Stock [Member] Additional Paid-in Capital Additional Paid-in Capital [Member] Accumulated Other Comprehensive Earnings (Loss) AOCI Attributable to Parent [Member] Retained Earnings (Accumulated Deficit) Retained Earnings [Member] ASU 2016-09 Accounting Standards Update 2016-09 [Member] Increase (Decrease) in Stockholders' Equity Increase (Decrease) in Stockholders' Equity [Roll Forward] Balance (in shares) Shares, Outstanding Balance Cumulative-effect of adoption of ASU Cumulative Effect of New Accounting Principle in Period of Adoption Adjusted balance (in shares) Stockholders Equity Including Portion Attributable To Noncontrolling Interest Adjusted Balance Amount of stockholders' equity including the portion attributable to noncontrolling interests, after the cumulative effect adjustment of a new accounting principle applied in the period of adoption. Adjusted balance Stockholders' Equity, Including Portion Attributable to Noncontrolling Interest, Adjusted Balance Share-based compensation APIC, Share-based Payment Arrangement, Increase for Cost Recognition Issuance of employee stock purchase plan shares (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of employee stock purchase plan shares Stock Issued During Period, Value, Employee Stock Purchase Plan Exercise of stock options (in shares) Stock Issued During Period Shares Stock Options and Warrants Exercised Number of share options and warrants (or share units) exercised during the current period. Exercise of stock options Stock Issued During Period Value Stock Options and Warrants Exercised Value of stock issued as a result of the exercise of stock options and warrants. Equity issued on conversion of convertible notes (in shares) Stock Issued During Period Shares Conversion of Convertible Notes The number of shares issued during the period upon the conversion of convertible notes. Equity issued on conversion of convertible notes Stock Issued During Period Value Conversion of Convertible Notes Value of stock issued during the period upon the conversion of convertible notes. Purchase of convertible note hedges, net of tax Purchases Of Convertible Note Hedges Net Of Tax Purchases of convertible note hedges, net of tax. Issuance of warrants Adjustments to Additional Paid in Capital, Warrant Issued Balance (in shares) Balance Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Statement of Cash Flows [Abstract] Name of Property [Axis] Name of Property [Axis] Name of Property [Domain] Name of Property [Domain] Acquisition of Biscayne Neurotherapeutics, Inc. Acquisition Of Biscayne Neurotherapeutics Inc [Member] Represents information related to the acquisition of Biscayne Neurotherapeutics, Inc. Cash flows from operating activities Net Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net earnings to net cash provided by operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Loss on extinguishment of debt Change in fair value of derivative liability Unrealized Gain (Loss) on Derivatives Depreciation and amortization Depreciation, Depletion and Amortization Noncash operating lease cost Noncash Operating Lease Cost Noncash Operating Lease Cost Amortization of premium/discount on marketable securities Investment Income, Net, Amortization of Discount and Premium Noncash interest expense Interest Expense Non Recourse Royalty Liability Interest incurred in the period on the non-recourse sale of future royalty liability arrangement that was charged against earnings. Noncash royalty revenue Share-based compensation expense Share-based Payment Arrangement, Noncash Expense Deferred income tax (benefit) provision Deferred Income Tax Expense (Benefit) Changes in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] Accounts receivable Increase (Decrease) in Accounts Receivable Inventories Increase (Decrease) in Inventories Prepaid expenses and other current assets Increase Decrease In Prepaid Deferred Expense And Other Current Assets Amount of increase (decrease) in prepaid expenses, and other current assets. Other noncurrent assets Increase (Decrease) in Other Noncurrent Assets Accounts payable Increase (Decrease) in Accounts Payable Accrued product returns and rebates Increase (Decrease) in Accrued Product Returns and Rebates Amount of increase (decrease) in product returns and rebates. Accrued expenses and other current liabilities Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities Income taxes payable Increase (Decrease) in Income Taxes Payable Deferred licensing revenue Increase (Decrease) in Deferred Licensing Revenue Represents the increase (decrease) during the reporting period, excluding the portion taken into income, in the liability reflecting licensing revenue yet to be earned for which cash or other forms of consideration was received or recorded as a receivable. Other liabilities Increase (Decrease) in Other Noncurrent Liabilities Net cash provided by operating activities Net Cash Provided by (Used in) Operating Activities Cash flows from investing activities Net Cash Provided by (Used in) Investing Activities [Abstract] Purchases of marketable securities Payments to Acquire Marketable Securities Sales and maturities of marketable securities Proceeds from Sale and Maturity of Marketable Securities Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Deferred legal fees Proceeds from Sale of Intangible Assets Deferred legal fees Payments to Acquire Intangible Assets Net cash used in investing activities Net Cash Provided by (Used in) Investing Activities Cash flows from financing activities Net Cash Provided by (Used in) Financing Activities [Abstract] Proceeds from issuance of convertible notes Proceeds from Convertible Debt Convertible notes issuance financing costs Proceeds from issuance of warrants Purchases of convertible note hedges Proceeds from issuance of common stock Proceeds from Issuance of Common Stock Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities Net change in cash and cash equivalents Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Cash and cash equivalents at beginning of year Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents Cash and cash equivalents at end of period Supplemental cash flow information: Supplemental Cash Flow Information [Abstract] Cash paid for interest on convertible notes Interest Paid, Excluding Capitalized Interest, Operating Activities Cash paid for Biscayne acquisition Payments to Acquire Businesses, Gross Income taxes paid Income Taxes Paid, Net Noncash investing and financing activity: Noncash Investing and Financing Items [Abstract] Conversion of convertible notes and interest make-whole Debt Conversion, Converted Instrument And Interest Make Whole Amount The value of the financial instrument(s) that the original debt is being converted into in a non-cash (or part non-cash) transaction as well as the interest make-whole. "Part non-cash" refers to that portion of the transaction not resulting in cash receipts or cash payments in the period. Deferred legal fees and fixed assets included in accounts payable and accrued expenses Non Cash Capitalized Cost Of Intangible Assets Represents the non-cash expenses related to intangible assets that were capitalized and shown within accrued expenses. Unsettled purchase of marketable securities included in accrued expenses Unsettled Purchase of Marketable Securities Included In Accrued Expenses The amount of unsettled purchase of marketable securities included in accrued expenses. Property and equipment additions from utilization of tenant improvement allowance Property And Equipment Additions From Utilization Of Tenant Improvement Allowance Property And Equipment Additions From Utilization Of Tenant Improvement Allowance Less Than 1 Year Debt Securities, Available-for-sale, Maturity, Allocated and Single Maturity Date, within One Year, Fair Value 1 year to 2 years Available For Sale Securities Debt Maturities After One Through Two Years Fair Value Fair value of available-for-sale debt securities maturing after the first year through the second fiscal year following the latest fiscal year. Excludes interim and annual periods when interim periods are reported on a rolling approach, from latest balance sheet date. 2 year to 3 years Available For Sale Securities Debt Maturities Two Years Through Three Years Fair Value Fair value of available-for-sale debt securities maturing in the second fiscal year through the third fiscal year following the latest fiscal year. Excludes interim and annual periods when interim periods are reported on a rolling approach, from latest balance sheet date. 3 years to 4 years Available For Sale Securities Debt Maturities Three Years Through Four Years Fair Value Fair value of available-for-sale debt securities maturing in the third fiscal year through the fourth fiscal year following the latest fiscal year. Excludes interim and annual periods when interim periods are reported on a rolling approach, from latest balance sheet date. Greater Than 4 Years Available For Sale Securities Debt Maturities, Thereafter, Fair Value Available For Sale Securities Debt Maturities, Thereafter, Fair Value Total Stock option and Stock Appreciation Rights Stock Option Stock Appreciation Rights [Member] Represents information related to stock option awards for employees and non-employees as well as stock appreciation rights. Assumptions used in estimating the fair value of each option award using the Black-Scholes option-pricing model Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract] Fair value of common stock (in dollars per share) Share Price Expected volatility, minimum (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum Expected volatility, maximum (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum Dividend yield (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected term Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Risk-free interest rate, minimum (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Risk-free interest rate, maximum (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Expected forfeiture rate (as a percent) Share Based Compensation Arrangement by Share Based Payment Award Fair Value Assumptions Expected Forfeiture Rate Represents the expected forfeiture rate assumption used in estimating the fair value of award. Number of Options and SAR Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Outstanding at the beginning of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Exercised (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Forfeited (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Outstanding at the end of the period (in shares) Vested and expected to vest (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Exercisable (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Weighted-Average Exercise Price Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Outstanding at the beginning of the period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Granted (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Exercised (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Forfeited (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Outstanding at the end of the period (in dollars per share) Vested and expected to vest (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Exercisable (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Weighted-Average Remaining Contractual Term (in years) Share Based Compensation Arrangement by Share Based Payment Award Options Weighted Average Remaining Contractual Term [Abstract] Outstanding at the end of the period Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Vested and expected to vest Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Aggregate Intrinsic Value (in thousands) Share Based Compensation Arrangement By Share Based Payment Award Options Aggregate Intrinsic Value [Abstract] n/a Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value Exercised Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value Vested and expected to vest Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value Share-based payments, additional disclosure Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract] Total unrecognized compensation expense Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Weighted-average period over which total unrecognized compensation expense is expected to be recognized Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Weighted-average, grant-date fair value of options granted (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Total fair value of the common stock vested Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value Cash paid for operating leases Operating Lease, Payments Cash paid for operating leases Operating Leases, Rent Payments Operating Leases, Rent Payments Lease assets and tenant receivables obtained for new operating leases Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Fixed lease cost Operating Lease, Fixed Lease, Cost Amount of fixed lease cost, excluded from lease liability, recognized when obligation for payment is incurred for operating leases. Variable lease cost Operating Lease, Variable Lease, Cost Amount of variable lease cost, excluded from lease liability, recognized when obligation for payment is incurred for operating leases. Total operating leases cost Operating Lease, Cost Intangible Assets Intangible Assets Disclosure [Text Block] Earnings per Share Earnings Per Share [Text Block] Raw materials Inventory, Work in Process and Raw Materials, Net of Reserves Work in process Inventory, Work in Process, Net of Reserves Finished goods Inventory, Finished Goods, Net of Reserves Total inventories Quarterly Financial Information (unaudited) Quarterly Financial Information [Text Block] Schedule of inventories Schedule of Inventory, Current [Table Text Block] Additional disclosures Intangible Assets, Net (Excluding Goodwill) [Abstract] Amortization expense Amortization of Intangible Assets Anticipated annual amortization expense for the next five years Finite-Lived Intangible Assets, Net, Amortization Expense, Fiscal Year Maturity [Abstract] 2020 Finite-Lived Intangible Assets, Amortization Expense, Next Twelve Months 2021 Finite-Lived Intangible Assets, Amortization Expense, Year Two 2022 Finite-Lived Intangible Assets, Amortization Expense, Year Three 2023 Finite-Lived Intangible Assets, Amortization Expense, Year Four 2024 Finite-Lived Intangible Assets, Amortization Expense, Year Five Deferred tax assets: Components of Deferred Tax Assets [Abstract] Convertible bond hedge Deferred Tax Assets Convertible Bond Hedge The tax effect, as of the balance sheet date, of the amount of the estimated future tax deductions arising from a convertible bond hedge, which can only be deducted for tax purposes when relevant losses are realized or actual obligations are incurred, and which can only be realized if sufficient tax-basis income is generated in future periods to enable the deduction to be taken. Accrued product returns and rebates Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Accrued Liabilities Accrued compensation and stock based compensation Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits Non-recourse liability related to sale of future royalties Deferred Tax Assets Royalty Revenue Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from royalty income. Research and development credit carryforwards Deferred Tax Assets, Tax Credit Carryforwards, Research Amortization of intangibles Deferred Tax Asset, Amortization Amount of deferred tax asset amortization. Net operating loss carryforwards Deferred Tax Assets, Operating Loss Carryforwards Operating lease liability Deferred Tax Assets, Operating Lease Liability Deferred Tax Assets, Operating Lease Liability Inventory Deferred Tax Assets, Inventory Alternative Minimum Tax (AMT) credit Deferred Tax Assets, Tax Credit Carryforwards, Alternative Minimum Tax Other Deferred Tax Assets, Other Total deferred tax assets Deferred Tax Assets, Gross Less: valuation allowance Deferred Tax Assets, Valuation Allowance Total deferred tax asset, net of valuation allowance Deferred Tax Assets, Net of Valuation Allowance Deferred tax liability: Components of Deferred Tax Liabilities [Abstract] Debt discount on 2023 Notes Deferred Tax Liabilities Debt Discount on Convertible Notes Amount of deferred tax liability attributable to taxable temporary differences from debt discount on convertible notes. Patent infringement legal costs Deferred Tax Liabilities Infringement Legal Cost Amount of deferred tax liability attributable to taxable temporary differences from Infringement legal cost. Operating lease assets Deferred Tax Liability, Operating Lease Assets Deferred Tax Liability, Operating Lease Assets Depreciation Deferred Tax Liabilities, Property, Plant and Equipment IRC Section 481(a) liability Deferred Tax Liabilities 481a Adjustment Amount of deferred tax liability attributable to taxable temporary differences related to adjustments to taxable income pursuant to Section 481(a). Unrealized gain on marketable securities Deferred Tax Liabilities, Unrealized Gain On Marketable Securities Deferred Tax Liabilities, Unrealized Gain On Marketable Securities Total deferred tax liabilities Deferred Tax Liabilities, Gross Net deferred tax assets Deferred Tax Assets, Net Number of commercial products Number Of Proprietary Commercial Products The number of proprietary commercial products market by the company. Income Statement Location [Axis] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] Selling, general and administrative Selling, General and Administrative Expenses [Member] Concentration of Credit Risk Advertising Expense Marketing and Advertising Expense [Abstract] Advertising costs Advertising Expense Income Taxes Income Tax Disclosure [Text Block] Accrued Expenses and Other Current Liabilities Accounts Payable and Accrued Liabilities Disclosure [Text Block] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table] Research and development Research and Development Expense [Member] Share-based Payments Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Share-based compensation recognized Share-based Payment Arrangement, Expense